SCREENING OF IN VITRO-PRODUCED CATTLE EMBRYOS TO ASSESS INCIDENCE AND CHARACTERISTICS OF UNBALANCED CHROMOSOMAL ABERRATIONS

Screening of in vitro-produced cattle embryos to assess incidence and characteristics of unbalanced chromosomal aberrations

In cattle, pregnancy rates of in vitro-produced embryos are lower than those of in vivo-produced embryos.One of the reasons may be the increase in chromosomal aberrations due to in vitro maturation and fertilization of the oocyte.Currently, embryo transfer is commonly applied in nucleus cattle breeding programs, and the embryos are genotyped for ge

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A case of conjunctival precursor T cell lymphoblastic lymphoma presenting with salmon colored conjunctival mass

Purpose: T-Lymphoblastic lymphoma (T-LBL) is a rare malignant tumor originated from precursor T-lymphocytes that differentiate to T lymphocytes.We report a rare case of T-LBL presenting with conjunctival mass as the first sign.Observations: A 61-year-old man presented with a right salmon colored conjunctival mass.A biopsy was performed, and histopa

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Functionally overlapping intra- and extralysosomal pathways promote bis(monoacylglycero)phosphate synthesis in mammalian cells

Abstract Bis(monoacylglycero)phosphate (BMP) is a major phospholipid constituent of intralumenal membranes in late endosomes/lysosomes, where it regulates the degradation and sorting of lipid cargo.Recent observations suggest that the Batten disease-associated protein CLN5 functions as lysosomal BMP synthase.Here, we show that transacylation reacti

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